WebApr 19, 2024 · Ototoxicity, which may be more pronounced in children, and is manifested by tinnitus, and/or loss of high frequency hearing and occasionally deafness, is significant. Anaphylactic-like reactions to PLATINOL have been reported. Facial edema, bronchoconstriction, tachycardia, and hypotension may occur within minutes of … WebApr 11, 2024 · Toxicity of intracarotid etoposide phosphate and carboplatin was reported in a 52-year old-male patient with glioblastoma multiforme. Citation 7 After 7 h of drug administration, it was observed that non-pupillary block angle-closure glaucoma developed secondary to uveal effusion in the ipsilateral eye (relieved by cycloplegia).
Full article: Management of diplopia due to chemotherapy toxicity …
WebJun 3, 2024 · Acute overdosage with cisplatin injection may result in renal failure, hepatic failure, hearing loss, ocular toxicity, myelosuppression, nausea and vomiting, and neuritis. WebJun 23, 2024 · Careful monitoring by audiometry should be performed prior to initiation of therapy and prior to subsequent doses of cisplatin. Vestibular toxicity has also been reported. (see section 4.8). ... deafness, ocular toxicity (including detachment of the retina), significant myelosuppression, untreatable nausea and vomiting and/or neuritis. An ... easter story teaching ideas
Cisplatin Side Effects: Common, Severe, Long Term
WebDec 13, 2024 · Also, ocular sections were evaluated histopathologically. Bromelain demonstrated a dose-dependent protective effect in cisplatin-induced toxicity by regulating oxidative stress, inflammation, and tissue damage. Our results suggested that bromelain may be a potential adjuvant that can protect the eye from cisplatin-induced toxicity. … WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class … WebThe main drugs with retinal toxicities are interferon alpha 2b, denileukin diftitiox, and the monoclonal antibodies, ipilimumab and trastuzumab (Table 2). Table 2: Biologics and Associated Retinal Toxicities Interferon alpha 2b This is a recombinant protein widely used in the treatment of inflammatory and infectious diseases, such as hepatitis C. culinary school virginia beach